Professor YK Lee’s MEMS/NEMS Group

Project --- The Latest Projects from the lab

Research Publications

Author(s)   Title
Y.-K. Lee   "Lyapunov Exponents of a Micro Chaotic Mixer, International Journal of Nonlinear Sciences and Numerical Simulation, Vol. 3, No.3-4, pp.561-563, 2002.
P.K. Wong, Y-.K. Lee and C.M. Ho   "Deformation of DNA Molecules by Hydrodynamic Focusing, accepted by Journal of Fluid Mechanics, Vol. 497, pp.55-65, 2003.
X. Niu and Y.-K. Lee   "Efficient Spatial-temporal Chaotic Mixing in Microchannels," Journal of Micromechanics and Microengineering, Vol. 13, No. 3, pp.454-462, 2003.
P. G. Deng, Y.-K. Lee and P. Cheng   "The Growth and Collapse of a Micro-bubble under Pulse Heating," International Journal of Heat and Mass Transfer, Vol. 46, No.21, pp.4041-4050, 2003.
A.S.W. Ng, W.L.W. Hau, Y.-K. Lee and Y. Zohar   "Electrokinetic Generation of Micro Vortex Patterns in a Microchannel Liquid Flow," Journal of Micromechanics and Microengineering, Vol. 14, No. 2, pp.247-255, 2004.
P.G. Deng, Y.-K. Lee and P. Cheng   "Micro Bubble Dynamics in DNA Solutions," Journal of Micromechanics and Microengineering, Vol. 14, No. 5, pp.693-701, 2004.
A. Dodge, M.-C. Jullien, X. Niu, F. Okkel, Y.-K. Lee and P. Tabeling   "An Example of a Chaotic Micromixer: the Channel-Micromixer," Comptes Rendus Physique (one Journal of French Academy of Science), Vol. 5, No. 5, pp.557-563, 2004.
A.I.K. Lao, Y.-K. Lee and I.-M. Hsing    "Mechanistic Investigation of Nanoparticle Motion in Pulsed Voltage Miniaturized Electrical Field Flow Fractionation by In-Situ Imaging of Nanoparticle Motion," Analytical Chemistry, Vol. 76, No. 10, pp.2719-2724, 2004.
P. Deng, Y.-K. Lee and P. Cheng   "Measurements of Micro Bubble Nucleation Temperatures in DNA Solution," Journal of Micromechanics and Microengineering, Vol. 15, No. 3, pp.564-574, 2005.
H. He, D.C. Chang and Y.-K. Lee   "Micro Pulsed Radio-Frequency Electroporation Chip," Bioelectrochemistry, Vol. 68, No. 1, pp.89-97, 2006.
T.F. Yu, Y.-K. Lee, M. Wong and Y. Zohar   "Fluid Flow in Microchannels with Cavities," Journal of Microelectrochemical Systems (JMEMS), Vol. 14, No. 6, pp.1-14, 2005.
M. Lee, L.S.L. Cheung, Y.-K. Lee and Y. Zohar   "Height Effect on Nucleation-Site Activity and Size-Dependent Bubble Dynamics in Microchannel Convective Boiling," Journal of Micromechanics and Microengineering, Vol. 15, No. 11, pp.1-9, 2005. 
X. Niu, W. Wen and Y.-K. Lee   "Electrorheological-fluid-based Microvalves," Applied Physics Letters, Vol. 87, 243501 (1-3), 2005.
L. M. Lee, W.L.W. Hau, Y.-K. Lee and Y. Zohar   "In-plane Vortex Flow in Microchannel Generated by Electroosmosis with Patterned Surface Charge," Journal of Micromechanics and Microengineering, Vol. 16, No. 1, pp.17-26, 2006.
P. Deng, Y.-K. Lee and P. Cheng   "An Experiemntal Study of Heater Size Effect on Micro Bubble Generation," International Journal of Heat and Mass Transfer, 2006 (in press).
Z. Jia, Y.-K. Lee, Q. Fang and C.W. Huie   "Video Imaging of Sample Zone Narrowing and Dispersion in a Glass Microchip: the Effect of Organic Solvent (Acetonitride)-salt Mixtures in the Sample Matrix and Surfactant Micelles in the Running Buffer," Electrophoresis, 2006 (in press).
Y.C. Chan, Y.-K. Lee and Y. Zohar   "High-throughput Design and Fabrication of an Integrated Microsystem with High Aspect-Ratio Sub-Micron Pill Arrays for Free-Solution Micro Capillary Electrophoresis," Journal of Micromechanics and Microengineering,  2006 (in press).
X. Cao, W.-J. Chiang, Y.-C. King and Y.-K. Lee   "Design and Fabrication of Integrated Vibration Power Generator System for Micro Sensor Networks," submitted to Sensors and Actuators A: Physical, 2005. 
P. Deng, Y.-K. Lee and P. Cheng   "Two-dimensional Micro Bubble Actuator Array to Enhance the Efficiency of Molecular Beacon Based DNA Micro Biosensor," Biosensors and Bioelectronics, Vol. 21, No. 8, pp.1443-1450, 2006/
L.M. Lee, W. L.W. Hau, Y.-K. Lee, Y. Zohar
"In-plane Vortex Flow in Microchannels Generated by Electroosmosis with Patterned Surface Charge,"
Journal of Micromechanics and Microengineering, Vol. 16, No. 1, pp.17-26, 2006. Abstract
X. Niu, W. Wen and Y.-K. Lee
Electrorheological-fluid-based Microvalves,
Applied Physics Letters
, Vol. 87, 243501 (1-3), 2005. Abstract
P. Deng, Y.-K. Lee and P. Cheng
"An Experimental Study of Heater Size Effect on Micro Bubble Generation,"
Intl. J. Heat and Mass Transfer, Vol. 49,No. 15-16, pp.2535-2544, 2006.
Z. Jia, Y.-K. Lee, Q. Fang and C. W. Huie
"Video Imaging of Sample Zone Narrowing and Dispersion in a Glass Microchip: the Effect of Organic Solvent(Acetonitrile)-salt Mixtures in the Sample Matrix and Surfactant Micelles in the Running Buffer,"
Electrophoresis , Vol. 27, No.5-6, pp.1104-1111, 2006.
Y. C. Chan, Y.-K. Lee and Y. Zohar
"High-throughput Design and Fabrication of an Integrated Microsystem with High Aspect-Ratio Sub-Micron Pillar Arrays for Free-Solution Micro Capillary Electrophoresis,"
Journal of Micromechanics and Microengineering, Vol. 16, No. 4, pp. 699-707, 2006.
B. Xu, Y.-K. Lee, Q.H. Jin, J.L. Zhao and C.M. Ho
"Multi-layer SU-8 Microdispenser for Microarray Assay,"
Sensors and Actuators A: Physical, 2006 (in press).
H. He, D. C. Chang and Y.-K. Lee
"Using a Micro Electroporation Chip to Determine the Optimal Physical Parameters in the Uptake of Biomolecules in HeLa Cells,"
Bioelectrochemistry, Vol. 71, pp.80-85, 2006.
X. Cao, W.-J. Chiang, Y.-C. King and Y.-K. Lee
"Design and Fabrication of Integrated Vibration Power Generator System for Micro Sensor Networks,"
IEEE Transactions on Power Electronics, 2006 (in press).
Y.-K. Lee, L.M. Lee, W.L.W. Hau and Y. Zohar.
Electrokinetically-driven Out-of-plane Vorticies in a Microchannel Liquid Flow Using Patterned Surface Charge,
Journal of Microelectromechanical Systems, 2006 (in press).
Y.-K. Lee, C. Shih, P. Tabeling and C.M. Ho
Experimental Study and Nonlinear Dynamic Analysis of Time-periodic Micro Chaotic Mixers,
Journal of Fluid Mechanics, 2006 (accepted in Sep 2006, in press).
M. Lee, L.S.L. Cheung, Y.-K. Lee and Y. Zohar
"Design, Fabrication and Characterization of a Thermal Microsystem Integrated with Pressure and Temperature Microsensors," in progress.

Conference Presentations

Author   Presentation Title
Y.-K. Lee, C. Shih, P. Tabling, C.M. Ho   "Characterization of Mixing Process in a Microchannel Flow,"presented at 52-th Annual Meeting of American Physical Society, Division of Fluid Dynamics, Nov., New Orleans, 1999.
Y.K. Lee, U.C. Yi, F.G. Tseng, C.J. Kim and C.M. Ho   "Fuel Injection by a Thermal Microinjector," Proceedings of MEMS, ASME International Mechanical Engineering, Nashville, Tennessee, Nov, pp. 419-425. 1999.
Y.-K. Lee, P. Tabeling, C. Shih and C.M. Ho   "Characterization of a MEMS-Fabricated Mixing Device," Proceeding of MEMS, ASME International Mechanical Engineering Congress and Exposition, Orlando, Florida, Nov, pp.505-511, 2000.
Y.-K. Lee, J. Deval, P. Tabeling, and C.M. Ho   "Chaotic Mixing in Electrokinetically Pressure Driven System Flows," IEEE 14th International Conference on Micro Electro Mechanical System (MEMS 2001), Interlaken, Switzerland, pp.483-486, 2001.
P.K. Wong, Y.-K. Lee, C.H. Ho   "Dynamics of DNA Molecules in Microchannel Flow," presented at 2nd University of California-wide Bioengineering Symposium, May 6-7, 2001.
Y.-K. Lee, A.S.W. Ng, L.M. Lee, Y. Zohar   "Micro Vortex Generation in Microchannel Liquid Flow," presented at 55-th Annual Meeting American Physical Society, Division of Fluid Dynamics, Nov., Dallas, 2002.
Y. Zohar, Z.T.F. Yu, Y.-K. Lee   "Hele-Shaw Flow in a Microchannel with Cavities," presented at 55-th Annual Meeting of American Physical Society, Division of Fluid Dynamics, Nov., Dallas, 2002.
W.L.W. Hau, L.M. Lee, Y.-K. Lee, M. Wong and Y. Zohar   "Experimental Investigation of Electrokinetically Generated In-Plane Vorticity in a Microchannel," Transducer'03 (the 12th Intl. Conf. on Solid-State Sensors, Actuators and Microsystems), Boston, pp.651-654, 2003.
A. S. W. Ng, W.L.W. Hau, Y.-K. Lee and Y. Zohar   "Numerical Simulations of Electrokinetically Generated Micro Vortices in Microchannels," Transducer'03 (the 12th Intl. Conf. on Solid-State Sensors, Actuators and Microsystems), Boston, pp.1887-1890, 2003.
P.G. Deng, Y.-K. Lee and P. Cheng   "Design and Characterization of A Micro Single Bubble Actuator ," Transducer'03 (the 12th Intl. Conf. on Solid-State Sensors, Actuators and Microsystems), Boston, pp.647-650, 2003.
X. Niu, Y.-K. Lee   "Finite Time Lyapunov Exponent for Micro Chaotic Mixer Design ," ASME IMECE'03, Washington DC, Nov. 16-21, 2003 (IMECE2003-41389).
W.L.W. Hau, L.M. Lee, Y.-K. Lee and Y. Zohar   "Electrically Driven Vortical Motion for Mixing of Liquids in a Microchannel ," Micro TAS 2003, Oct 5-9, Squaw Valley, California, USA, pp. 491-494, 2003.
P.K. Wong, T.H. Wang, Y.-K. Lee, C. Shih and C.M. Ho   "Visualization of Nanoscale Biomolecules in Micro Fluidic Devices," presented at the 7th Asian Symposium on Visualization, May 26-30, Singapore, 2003.
A. I.K. Lao, T.P. Duan, Y.-K. Lee and I.M. Hsing   "Microfabricated Flow Fractionation Device Assisted by a Pulse Electric Field: In-situ Visualization and its Application for DNA Separation," submitted to American Institute of Chemical Engineers 2003 Annual Meeting, Nov. 16-21, San Francisco, CA, USA.
M. Lee, L.S.L. Cheung, Y.-K. Lee, M. Wong, Y. Zohar   "Height Effect on Nucleation-Site Activity in Microchannel Convective Boiling," IEEE MEMS 2004, Maastricht, Netherlands, Jan 25-29, pp.300-303, 2004.
Z.T.F. Yu, Y.-K. Lee, M. Wong, Y. Zohar   "Size-Dependent Flow Separation in Microchannels with Cavities," IEEE MEMS 2004, Maastricht, Netherlands, Jan 25-29, pp.296-299, 2004.
P.G. Deng, Y.-K. Lee and P. Cheng   "Viscosity Effect on Micro Bubble Actuator in ssDNA Solutions," IEEE MEMS 2004, Maastricht, Netherlands, Jan 25-29, pp.292-295, 2004.
P.G Deng, Y.-K. Lee and P. Cheng   "Transient Micro Bubble Nucleation in Bio-solutions," accepted by International Conference on Multiphase Flow (ICMF 2004), Yokohama, Japan, May 31-June 3, 2004.
F. Yang, H.-Q. He and Y.-K. Lee   "Parametric Study of Pulsed Radio-Frequency Electroporation on Microchips at the Single-cell Level," accepted by Micro TAS 2004, Malmo, Sweden.
P.G Deng, Y.-K. Lee and P. Cheng   "Characterization of an Integrated Self-sensing Submicron Bubble Actuator," submitted to Asia-Pacific Conf. of Transducers and Micro-Nano Tech., Sapporo, Japan, July 4-7, 2004.
Y.-K. Lee  

"Complex Electroosmotic Microflow with Surface Charge Patterning," The 7th Asian Conference on Analytical Sciences (Asianalysis VII), July 28-31, 2004 (invited).

F. Yang, Huiqi He, D.C. Chang and Y.-K. Lee  

"Parametric Study of Pulsed Radio-Frequency Electroporation on Microchip at the Single-cell Level,"The 8th International Conference on Miniaturized Systems for Chemistry and Life Sciences (Micro TAS 2004), Malmo, Sweden, 26-30 Sep, Vol. 2, pp. 79-81,2004.Abstract.

Y.-K. Lee  

"Electrokinetic Vortex Dynamics in Surface Charge Patterned Microchannels," The 6th World Congress of Computational Mechanics (WCCM VI), Beijing, China, 2004 (invited).

M. Lee, Y.-K. Lee, M. Wong and Y. Zohar  

"Fabrication and Characterization of an Integrated Thermal Microsystem," IEEE MEMS 2005, Miami, FL, USA, pp.610-613, 2005. Abstract

L. M. Lee, Y.-K. Lee and Y. Zohar  

"Unsteady In-Plane Vortex Motion in a Microchannel Liquid Flow," IEEE MEMS 2005, Miami, pp.734-737, 2005. Abstract

L.S.L. Cheung, Y.-K. Lee, M. Wong and Y. Zohar  

"Size-Dependent Bubble Dynamics in a Microchannel Heat Sink," IEEE MEMS 2005, Miami, FL, USA, pp.670-673, 2005. Abstract

P. Deng, Y.-K. Lee and P. Cheng,  

"Scaling Effects of Micro Bubble Actuators," Transducers 2005, Seoul, Korea, Vol. 2, pp. 1267-1271, Jun 5-9, 2005. Abstract

X. Niu, Weijia Wen and Y.-K. Lee  

"Micro Valves Using Nanoparticles-based Giant Electrorheological Fluid," Transducers 2005, Seoul, Korea, Vol. 1, pp.652-655, 2005. Abstract

E.K.L. Chan, C.K.Y. Wong, M. Lee, M.M.F. Yuen, Y.-K. Lee  

"Using PDMS Micro-transfer Moulding for Polymer Flip Chip Packaging on MEMS," the 55th Electronic Components and Technology Conference (ECTC), Lake Buena Vista, FL, USA, May 31-June 3, pp.1071-1076, 2005.

Y.-K. Lee and P. Deng  

"Bubble Actuator Enhanced DNA Micro Biosensor,"Proceeding of the 2005 IEEE International Conference on Robotics and Biomimetics ( IEEE Robio'05), Hong Kong and Macau, pp.752-756, Jun 29-Jul 3, 2005. Abstract

Y. C. Chan, Y.-K. Lee, M. Wong and Y. Zohar  

"High-Throughput Fabrication of Sub-Micron Pillar Arrays for Free-Solution DNA Electrophoresis without E-beam Lithography," Proceeding of the 2005 IEEE International Conference on Robotics and Biomimetics (IEEE Robio'05), Hong Kong and Macau, pp.101-104, Jun 29-Jul 3, 2005 Abstract

W.L.W. Hau, P.K Leung, L.M. Lee, Y.-K. Lee and Y. Zohar  

"Electrokinetically-Driven Micro Mixer with a Novel Surface-Charge Pattern ," Proceeding of the 2005 IEEE International Conference on Robotics and Biomimetics (IEEE Robio'05), Hong Kong and Macau, pp.783-787, Jun 29-Jul 3, 2005

H. He, D.C. Chang and Y.-K. Lee  

"Large-Scale Parametric Study of Electroporation in Cancer Cells to Construct Phase Diagrams Using Micro Cell-Array Chips," The 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences (Micro TAS 2005), Boston, USA, pp.382-384, Oct 9-13, 2005. Abstract

Y.C. Chan, Y.-K. Lee, M. Wong and Y. Zohar  

"Effect of Sub-Micron Pillar Array on DNA Kinetics in a Free-Solution Capillary Electrophoresis Microsystem," Micro TAS 2005, Boston, USA, pp.337-339, Oct 9-13, 2005. Abstract

C.W. Huie, Q. Li, Z. Jia, Y.-K. Lee, Q. Fang and Z.L. Fang  

"Effect of Organic Solvent-Salt Mixtures on Sample Preconcentration in Capillary and Microchip Electrophoresis," The 8th Asian Conference on Analytical Science (Asianalysis VIII), Taipei, Taiwan, Oct 16-20, 2005.

M. Lee, Y.-K. Lee and Y. Zohar  

"Two-Phase Flow in Microchannel Heat Sink with Nearly Uniform Heat Flux Boundary Condition," IEEE NEMS 2006, Zuhai, China, Jan 18-21, pp. 754-758, 2006.

P.K. Leung, P. Deng, Y.-K. Lee  

"Comparative Study of Size Effect of Micro Bubble Dynamics by Sub-100 Microsecond and Milisecond Pulse Heating," IEEE NEMS 2006, Zhuhai, China, Jan 18-21, pp.525-529, 2006.

X. Niu, Y.-K. Lee, Liyu Liu and W. Wen  

"Micro valve and chaotic mixer driven by electrorheological fluid," IEEE NEMS 2006, Zhuhai, China, Jan 18-21, pp.1254-1257, 2006.

Y.C. Chan, Y.-K. Lee and Y. Zohar  

"Nonlinear Electrophoretic Mobility of Large DNA Molecules in Microsystem with Sub-Micron Pillar Arrays,"IEEE MEMS 2006, Istanbul, Turkey, pp.438-441,Jan 22-26, 2006.

M. Lee, L.S.L. Cheugn, Y.-K. Lee and Y. Zohar  

"Boundary Conditions and Integrated Sensors in Microchannel Convective Heat Transfer," the 4th International Conference on Nanochannels, Microchannels and Minichannels (ASME ICNMM 2006), Limerick, Ireland, June 19-21, 2006 (No. ICNMM2006-96117) (keynote paper).

X. Cao and Y.-K. Lee  

"Design and Fabrication of Mini Vibration Power Generator," IEEE International Conference on Information Acquisition (IEEE ICIA 2006), Weihai, China, pp.91-95, Aug 20-23, 2006.

H. He, Y.-K. Lee and D.C. Chang  

"Molecular Size Effect on Micro Electroporation by Using Microchip with a Three-dimensional Electrode Array," The 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences (Micro TAS 2006), Tokyo, Japan, pp.28-30, 2006.

M. Lu, A. Bermak, Y.-K. Lee  

"Fabrication Technology of Piezoresistive Conductive PDMS for Micro Fingerprint Sensors," IEEE MEMS 2007, Kobe, Japan, Jan 21-25,2007 (in press).

Y.C. Chan, Y.-K. Leeand Y. Zohar  

"Pillar Size Effect on DNA Electrophoresis in Microchip with Sub-micron Pillar Arrays," IEEE MEMS 2007, Kobe, Japan, Jan 21-25,2007 (in press).

M. Lee, Y.-K. Lee and Y. Zohar   "Two-Phase Flow Oscillations in Microchannel Convective Boiling," IEEE MEMS 2007, Kobe, Japan, Jan 21-25, 2007 (in press)
H. He, D.C. Chang and Y.-K. Lee  

"Nonlinear Transmembrane Current Response of Micro Electroporation for Human Cancer Cells," IEEE NEMS 2007, Bangkok, Thailand, Jan 16-19, 2007.

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Prof. YK Lee’s MEMS/NEMS Group
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